Position:
Post-Doc
Seit:
April 2011
Forschungsfelder:
Physiologie der Testikularzellen
Methoden:
Elektrophysiologie, Ca2+-Imaging, CLARITY, Zellkultur, STED Microskopie
Kontakt:
d.fleck@sensorik.rwth-aachen.de
Tel.: +49 (0)241 / 80-21383
ResearchGate
Publikationen:
| Christoph Hamacher, Rudolf Degen, Melissa Franke, Victoria K. Switacz, David Fleck, Raghu Ram Katreddi, Andres Hernandez-Clavijo, Martin Strauch, Nao Horio, Enno Hachgenei, Jennifer Spehr, Stephen D. Liberles, Dorit Merhof, Paolo E. Forni, Geraldine Zimmer-Bensch, Yoram Ben-Shaul, and Marc Spehr (2024) A revised conceptual framework for mouse vomeronasal pumping and stimulus sampling, Current Biology 34, https://doi.org/10.1016/j.cub.2024.01.036 |
| Fleck D, Kenzler L, Mundt N, Strauch M, Uesaka N, Moosmann R, Bruentgens F, Missel A, Mayerhofer A, Merhof D, Spehr J, Spehr M (2021) ATP activation of peritubular cells drives testicular sperm transport. eLIFE 10:e62885 DOI: 10.7554/eLife.62885 |
| Puelles VG, Fleck D, Ortz L, Papadouri S, Strieder T, Böhner AMC, van der Wolde JW, Vogt M, Saritas T, Kuppe C, Fuss A, Menzel S, Klinkhammer BM, Müller-Newen G, Heymann F, Decker L, Braun F, Kretz O, Huber TB, Susaki EA, Ueda HR, Boor P, Floege J, Kramann R, Kurts C, Bertram JF, Spehr M, Nikolic-Paterson DJ, Moeller MJ (2019) Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis. Kidney International 96: 505-516 DOI: 10.1016/j.kint.2019.02.034 |
| Zhang Y, Vargas Cifuentes L, Wright K, Bhattarai J, Mohrhardt J, Fleck D, Janke E, Jiang C, Cranfill S, Goldstein N, chreck M, Moberly A, Yu Y, Arenkiel B, Betley J, Luo W, Stegmaier J, Wesson D, Spehr M, Fuccillo M, Ma M (2021) Ventral striatal islands of Calleja neurons control grooming in mice. Nature Neuroscience 24 (12). DOI: 10.1038/s41593-021-00952-z |
| Marom K, Horesh N, Abu-Snieneh A, Dafni A, Paul R, Fleck D, Spehr M, Ben-Shau Yl (2019) The vomeronasal system can mediate novel stimulus response pairings. Cell Reports. DOI:10.1016/j.celrep.2019.03.042 |
| Gretenkord S, Kostka JK, Hartung H, Watznauer K, Fleck D, Minier-Toribio A, Spehr M, Hanganu-Opatz IL (2019) Coordinated electrical activity in the olfactory bulb gates the oscillatory entrainment of entorhinal networks in neonatal mice. PLoS Biology 17: e2006994. DOI: 10.1371/journal.pbio.2006994 |
| Mohrhardt J, Nagel M, Fleck D, Ben-Shaul Y, Spehr M (2018) Signal detection and coding in the accessory olfactory system. Chemical Senses 43: 667-695. DOI: 10.1093/chemse/bjy061 |
| Walenta L, Fleck D, Fröhlich /, von Eysmondt H, Arnold G, Spehr J, Schwarzer JU, Köhn F-M, Spehr M, Mayerhofer A (2018) ATP-mediated events in peritubular cells contribute to sterile testicular inflammation. Scientific Reports 8: 1431. DOI: 10.1038/s41598-018-19624-3 |
| Pelz T, Drose DR, Fleck D, Henkel B, Ackels T, Spehr M, Neuhaus EM (2018) An ancestral TMEM16 homolog from Dictyostelium discoideum forms a scramblase. PLOS ONE13:e0191219. DOI: 10.1371/journal.pone.0191219 |
| Schneider RK, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, Van Strien PMH, Bindels EM, Heckl D, Büsche G, Fleck D, Müller-Newen G, Wongboonsin J, Ventura Ferreira M, Puelles VG, Saez-Rodriguez J, Ebert BL, Humphreys BD, Kramann R (2017) Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target. Cell Stem Cell 20: 785-800. DOI: 10.1016/j.stem.2017.03.008 |
| Fleck D, Mundt N, Bruentgens F, Geilenkirchen P, A Machado P, Veitinger T, Veitinger S, Engelhardt CH, Oldiges M, Spehr J, Spehr M (2016) Distinct purinergic signaling pathways in prepubescent mouse spermatogonia. The Journal of General Physiology 148: 253-271. DOI: 10.1085/jgp.201611636 |
| Gamper I, Fleck D, Barlin M, Spehr M, El Sayad S, Kleine H, Maxeiner S, Schalla C, Aydin G, Hoss M, Litchfield DW, Lüscher B, Zenke M, Sechi A (2015) GAR22β regulates cell migration, sperm motility and axoneme structure. Molecular Biology of the Cell 27: 277-294. DOI: 10.1091/mbc.E15-06-0426 |
