Position:
Leitende Wissenschaftlerin, RTG-Koordination
Seit:
Mai 2009
Forschungsfelder:
Neurophysiologie und Reproduktionsphysiologie
Methoden:
Elektrophysiologie, Live-Cell Imaging, Bewegungsanalyse, Sozialverhalten von Mäusen
Kontakt:
j.spehr@sensorik.rwth-aachen.de
Tel.: +49 (0)241 / 80-20803
ResearchGate
Publikationen:
| Christoph Hamacher, Rudolf Degen, Melissa Franke, Victoria K. Switacz, David Fleck, Raghu Ram Katreddi, Andres Hernandez-Clavijo, Martin Strauch, Nao Horio, Enno Hachgenei, Jennifer Spehr, Stephen D. Liberles, Dorit Merhof, Paolo E. Forni, Geraldine Zimmer-Bensch, Yoram Ben-Shaul, and Marc Spehr (2024) A revised conceptual framework for mouse vomeronasal pumping and stimulus sampling, Current Biology 34, https://doi.org/10.1016/j.cub.2024.01.036 |
| Walenta L, Fleck D, Fröhlich /, von Eysmondt H, Arnold G, Spehr J, Schwarzer JU, Köhn F-M, Spehr M, Mayerhofer A. ATP-mediated Events in Peritubular Cells Contribute to Sterile Testicular Inflammation. Scientific Reports 8: 1431. |
| Fleck D, Mundt N, Bruentgens F, Geilenkirchen P, A Machado P, Veitinger T, Veitinger S, Engelhardt CH, Oldiges M, Spehr J, Spehr M (2016) Distinct purinergic signaling pathways in prepubescent mouse spermatogonia. The Journal of General Physiology 148: 253-271. |
| Cichy A, Ackels T, Tsitoura C, Kahan A, Gronloh N, Söchtig M, Engelhardt CH, Ben-Shaul Y, Müller F, Spehr J, Spehr M (2015) Extracellular pH regulates excitability of vomeronasal sensory neurons. The Journal of Neuroscience 35: 4025-4039. |
| Schöbel N, Radtke D, Lübbert M, Gisselmann G, Lehmann R, Cichy A, Schreiner BS, Altmüller J, Spector AC, Spehr J, Hatt H, Wetzel CH (2012) Trigeminal ganglion neurons of mice show intracellular chloride accumulation and chloride-dependent amplification of capsaicin-induced responses. PLoS One |
| Fluegge D, Moeller LM, Cichy A, Gorin M, Weth A, Veitinger S, Cainarca S, Lohmer S, Corrazza S, Neuhaus EM, Baumgartner W, Spehr J, Spehr M (2012) Mitochondrial Ca2+ Mobilization is a key element in olfactory signaling. Nat. Neurosci.15: 754-762. |
| Veitinger S, Veitinger T, Cainarca S, Fluegge D, Engelhardt CH, Lohmer S, Hatt H, Corrazza S, Spehr J, Neuhaus EM, Spehr M (2011) Mitochondrial Ca Mobilization in Purinergic Mouse Sertoli Cell Signaling. J. Physiol. 589: 5033–5055. |
| Spehr J, Gelis L, Osterloh M, Oberland S, Hatt H, Spehr M, Neuhaus EM (2011) G-protein-coupled receptor signaling via Src kinase induces endogenous human transient receptor potential vanilloid type 6 (TRPV6) channel activation. J. Biol. Chem. 286: 13184-13192. |
| Spehr J,Hagendorf S, Weiss J, Spehr M, Leinders-Zufall T, Zufall F (2009) Ca2+-calmodulin feedback mediates sensory adaptation and inhibits pheromone-sensitive ion channels in the vomeronasal organ. J. Neurosci. 29:2125-2135. |
| Spehr M, Spehr J, Kelliher KR, Ukhanov K, Leinders-Zufall T, Zufall F (2006) Parallel processing of social signals by the mammalian main and accessory olfactory systems. Cell. Mol. Life Sci. CMLS 63: 1476-1484. |
| Spehr J, Spehr M, Hatt H, Wetzel CH. (2004) Subunit-specific P2X-receptor expression defines chemosensory properties of trigeminal neurons. Eur. J. Neurosci. 9:2497-510. |
| Paul J, Gottmann K, Lessmann V. (2001) NT-3 regulates BDNF-induced modulation of synaptic transmission in cultured hippocampal neurons. Neuroreport. 12:2635-9. |
