Dr. Jennifer Spehr

Senior Scientist, RTG coordination

Started in:
May 2009

Fields of Research:
Neurophysiology and Reproductive Physiology

Electrophysiology, Live-Cell Imaging, Motion Analysis, Mouse Social Behaviour

Tel.: +49 (0)241 / 80-20803

Selected Publications:

Fleck D, Mundt N, Bruentgens F, Geilenkirchen P, A Machado P, Veitinger T, Veitinger S, Engelhardt CH, Oldiges M, Spehr J, Spehr M (2016) Distinct purinergic signaling pathways in prepubescent mouse spermatogonia. The Journal of General Physiology 148: 253-271.
Cichy A, Ackels T, Tsitoura C, Kahan A, Gronloh N, Söchtig M, Engelhardt CH, Ben-Shaul Y, Müller F, Spehr J, Spehr M (2015) Extracellular pH regulates excitability of vomeronasal sensory neurons. The Journal of Neuroscience 35: 4025-4039.
Schöbel N, Radtke D, Lübbert M, Gisselmann G, Lehmann R, Cichy A, Schreiner BS, Altmüller J, Spector AC, Spehr J, Hatt H, Wetzel CH (2012) Trigeminal ganglion neurons of mice show intracellular chloride accumulation and chloride-dependent amplification of capsaicin-induced responses. PLoS One
Fluegge D, Moeller LM, Cichy A, Gorin M, Weth A, Veitinger S, Cainarca S, Lohmer S, Corrazza S, Neuhaus EM, Baumgartner W, Spehr J, Spehr M (2012) Mitochondrial Ca2+ Mobilization is a key element in olfactory signaling. Nat. Neurosci.15: 754-762.
Veitinger S, Veitinger T, Cainarca S, Fluegge D, Engelhardt CH, Lohmer S, Hatt H, Corrazza S, Spehr J, Neuhaus EM, Spehr M (2011) Mitochondrial Ca Mobilization in Purinergic Mouse Sertoli Cell Signaling. J. Physiol. 589: 5033–5055.
Spehr J, Gelis L, Osterloh M, Oberland S, Hatt H, Spehr M, Neuhaus EM (2011) G-protein-coupled receptor signaling via Src kinase induces endogenous human transient receptor potential vanilloid type 6 (TRPV6) channel activation. J. Biol. Chem. 286: 13184-13192.
Spehr J,Hagendorf S, Weiss J, Spehr M, Leinders-Zufall T, Zufall F (2009) Ca2+-calmodulin feedback mediates sensory adaptation and inhibits pheromone-sensitive ion channels in the vomeronasal organ. J. Neurosci. 29:2125-2135.
Spehr M, Spehr J, Kelliher KR, Ukhanov K, Leinders-Zufall T, Zufall F (2006) Parallel processing of social signals by the mammalian main and accessory olfactory systems. Cell. Mol. Life Sci. CMLS 63: 1476-1484.
Spehr J, Spehr M, Hatt H, Wetzel CH. (2004) Subunit-specific P2X-receptor expression defines chemosensory properties of trigeminal neurons. Eur. J. Neurosci. 9:2497-510.
Paul J, Gottmann K, Lessmann V. (2001) NT-3 regulates BDNF-induced modulation of synaptic transmission in cultured hippocampal neurons. Neuroreport. 12:2635-9.